Data Science Day @ Columbia University has ended
Columbia University’s Data Science Institute Presents:

Authors/Collaborators are listed in alphabetical order.

Back To Schedule
Wednesday, April 6 • 2:00pm - 4:30pm
Mapping Cells and Their Connections in Networks of the Brain Master Clock [P7]

Sign up or log in to save this to your schedule, view media, leave feedback and see who's attending!

Understanding the neural networks associated with specific brain functions is a challenge. The brain’s master clock, located in the suprachiasmatic nucleus (SCN), and made up of ~20,000 “clock cells”, presents an ideal system for exploring the relationship of cellular/molecular events to inter-connections among cells, and how these networks sustain the body’s daily rhythms. At the intracellular level, rhythmicity is produced by feedback loops involving daily rhythms in expression of “clock” genes and associated proteins. To determine whether or not all SCN cells are identical in their intracellular/molecular clocks, we designed programs to assess protein expression levels over days, over time of day, and in location of individual cells within the nucleus, using Mathematica. Our novel approach to analyzing neural networks yields evidence of both regional and cellular specialization of clock protein expression. The findings point to a new mechanism for encoding information in SCN networks.

Demo/Poster Presenter
avatar for Erica Mezias

Erica Mezias

Research Assistant, Cognitive Development Center, Barnard College
Erica Mezias is a senior at Barnard College majoring in Psychology.  She is currently working on a senior thesis in Neuroscience and Behavior in Dr. Rae Silver's Neurobiology lab where she investigates the molecular basis of circadian rhythms using novel computational methods... Read More →
avatar for Malini Riddle

Malini Riddle

Undergraduate Research Assistant, Neuroscience & Behavior, Barnard College
Malini is a junior at Barnard College majoring in cellular neuroscience. She works as a research assistant at Dr. Rae Silver's Neurobiology Lab at Barnard, where she studies circadian rhythms using quantitative computational methods that she helps to develop. Malini has  experience... Read More →

Demo/Poster Collaborator

Duncan Foley

Department of Economics, New School for Social Research

Joseph Lesauter

Senior Research Scientist in Psychology, Barnard College

Rae Silver

Helene L. and Mark N. Kaplan Professor of Natural and Physical Sciences, Columbia University

Wednesday April 6, 2016 2:00pm - 4:30pm EDT
Roone Arledge Auditorium Lerner Hall, Columbia University 2920 Broadway, New York, NY 10040

Attendees (1)